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Welcome to the Keloid Research Foundation
Established in 2011 by Dr. Michael H. Tirgan, the KRF is a 501 (C)(3), non for profit medical research and educational organization. The mission of KRF is to foster scientific research in keloid disorder and to promote education, advocacy, and service to those who suffer from this disorder. Donors can deduct contributions they make to KRF under IRC Section 170.
Keloid is a genetic skin disorder which results in excessive growth and formation of tumor-like areas in an otherwise healthy skin. Despite their benign nature, keloids may constitute severe aesthetic as well as functional problems that can negatively impact patients’ quality of life.
Keloids are mostly observed between ages of 10 and 30 years. There is no consensus on the best method of treatment for this condition; neither do we have any form of wholly satisfactory therapy. Keloids do not regress and are characterized by a high rate of recurrence after surgery or other forms of treatment. Indeed, surgical treatment often gives rise to even larger lesions. In addition, being a uniquely human condition, no animal study models are available.
Although a common medical condition, keloid disorder has been neglected by the research community. There are no statistics as to its incidence and prevalence, neither in the United States, nor elsewhere in the world. This disorder, although quite common and although at times very disabling, has not captured the interest of the research community and remains an area of unmet medical need.
It behaves quite similar to cancer, yet it does not metastasize to tissues outside skin (or maybe it does and we simply do not know about it).
KRF was formed to foster scientific research in this disease. To accomplish its goals, KRF will raise funds, increase awareness and bolster interest in this disease. We will not make any progress in this disease unless we dedicate the same kind of interest, effort and energy that we have dedicated to cancer research.
Understanding the Condition
What Is Keloid Disorder?
A keloid is far more than a raised scar. It is a genetic skin disorder that results in excessive growth and formation of tumor-like areas in otherwise healthy skin — behaving in some ways like cancer, yet, as far as is currently known, without metastasis beyond the skin.
Despite being benign, keloids can cause severe aesthetic and functional problems that negatively impact patients’ quality of life, and the disorder remains an area of unmet medical need with no reliable incidence data anywhere in the world.
Genetic in Origin
A genetic skin disorder — not an ordinary scar — resulting in tumor-like growth in otherwise healthy skin.
Ages 10–30 Most Affected
Keloids are mostly observed between ages of 10 and 30 years.
No Wholly Satisfactory Therapy
Keloids do not regress and recur at a high rate after surgery or other treatment.
No Animal Models
Being a uniquely human condition, no animal study models are available.
Explore KRF
Resources for Patients, Clinicians & Researchers
From treatment guidance to genomic research, explore the resources the Foundation has built for every corner of the keloid community.
Mission Statement
Learn about KRF’s founding mission and the goals driving its work.
Treatment Guidelines
Evidence-based guidance for the clinical management of keloid disorder.
Newly Diagnosed Patients
Guidance for patients who have just been diagnosed with keloid disorder.
Keloid Nomenclature
Standardized terminology for describing keloid disorder in research and clinical practice.
RECORD Criteria
Response Evaluation Criteria in patients with keloid disorder — a standardized outcomes framework.
Genomic Research
The Foundation’s work toward understanding the genetic basis of keloid disorder.
Take Action
Join the Effort Against a Neglected Disease
KRF depends on donors, members, and the patient community itself to move keloid research forward.
Become a Member
Join a growing international community of clinicians, researchers, and advocates working on keloid disorder.
Share Your Story
Every patient’s experience helps raise awareness. Share your encounter with keloid disorder with our community.
Join Us at the 7th International Keloid Symposium
Paris, France · June 17–19, 2027. Connect with clinicians, researchers, and advocates advancing keloid disorder care.