Scientific Agenda

Studies of the human genome and the genomes of many other organisms--hold great promise for approaches to medicine not even imagined a decade ago. The complete DNA sequence of keloid tissue will make it possible to define unique signatures for this entity. This situation has already been achieved for several bacteria and yeast, providing new opportunities for combating infectious diseases and understanding fundamental cell processes. Using rapidly evolving genomic technologies, a very powerful new tool to reveal the secrets of disease susceptibility and the mechanisms by which diseases develop, will create new opportunities for better understanding the pathology of keloids and new ways of treating this condition.

In the past few decades, we have learned that genetic changes lie at the root of all cancers. To be able to look into a single keloid cell, as routinely do in cancers, and read its molecular signature will allow us to determine what is different between a normal skin cell and a keloid cell and will lead to the development of highly specific, sensitive molecular targets and pathways that can be effectively blocked or inhibited with pharmaceutical products of today or tomorrow.

LATEST NEWS

    2nd International Keloid Symposium:

    (Januar 18, 2018) KRF is proudly announcing that the 2nd will be held on June 7-8, 2018 in Rome, Italy. Click on the image below to be directed to the symposium website.

    Notice of 501 (C)(3) Status:

    (February 1, 2017) Keloid Research Foundation has been determined by the US Internal Revenue Service (IRS) to be exempt from federal income tax under Internal Revenue Code (IRC) Section 501(C)(3). Donors can deduct contributions they make to KRF under IRC Section 170. Click here to view the 501(C)(3) Exemption Document.

    Journal of Keloid Research:

    (December 3, 2016)KRF is proud to announce establishment of Keloid Research, an open access scientific publication of the Keloid Research Foundation. Until now, keloid manuscripts have been published in a variety of journals. Our goal is to create a centralized publishing platform for all researchers who are passionate about this disorder, so that relevant clinical and laboratory research can be published in one place and under one umbrella. The journal is aiming to provide an international forum for the publication of original work, describing basic science, translational and clinical investigations in keloid disorder.

    Keloid Staging System:

    (August 19, 2016) In his most recent publication, "Neck Keloids: evaluation of risk factors and recommendation for keloid staging system" Dr. Tirgan has designed a staging system that allows for proper categorization and grouping of keloid patients into various stages.

    To assess each keloid patient properly, to better understand the natural history of this disorder, and to be able to compare future keloid study results among various patients groups, we clearly need a staging system that can allow us to describe the severity keloid disorder based on the size, location and/or extent of the keloidal lesions; as well as history of surgery or radiation therapy, and perhaps other factors that are currently unknown to us. Please click HERE to read more.