Keloid Treatment Guidelines

KRF® is dedicated to the development of a series of clinical practice treatment guidelines for medical management of keloid patients. These Guidelines are authored by KRF and endorsed by clinicians who agree with each Guideline and adhere to the Guideline in treating their own keloid patients.

By disseminating these Treatment Guidelines, KRF hopes to enhance and contribute to the education of physicians who treat keloid patients in order to improve the treatment outcomes.

Guidelines presented here are intended to provide recommendations for treatment of patients with common clinical presentations of keloid disorder. As you will notice throughout these Guidelines, not all keloid patients present in a similar manner. Every patient presents a unique problem. Therefore, the treatment for each keloid lesion should be customized for each patient. Obviously, the first instinct in a young person who develops a keloid lesion is to have that lesion surgically removed. As documented throughout these Guidelines, rushing into surgery will often result in worsening of the keloids - simply because keloid disorder is a progressive and multifocal disorder of the skin. Our better understanding of basic facts about this chronic genetic ailment will guide us to more effective treatment choices.

Help Us to Improve the Guidelines

Preparing the Guidelines is a tedious task. Each document has been reviewed and edited several times. If you notice any typo or other errors in any of these Guidelines, please take a moment to let us know by emailing a note to: ""

If you are a physician treating keloid patients and have reviewed our Guidelines, we would like to hear your thoughts and your input. Please email us at ""

KRF will gradually list and make the following guidelines available.

KRF Keloid Treatment Guidelines:

Treatment Modalities:

1- Intra-Lesional Triamcinolone
2- Intra-Lesional Chemotherapy
3- Cryotherapy
4- Magnetic Disks
5- Treatment Strategy

Keloid Treatment Guidelines by Site:

1- Ear Keloids
2- Facial Keloids
3- Scalp Keloids
4- Neck Keloids
5- Chest Keloids
6- Shoulder / upper arm keloids
7- Pubic keloids


The KRF Guidelines® are statements of evidence and consensus of the author and other keloid experts listed herein regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult with the KRF® Guidelines is expected to use independent medical judgment in the context of individual clinical circumstances to determine any patient's proper care or proper treatment.

Keloid Research Foundation® (KRF®) makes no representations or warranties of any kind regarding the content of these guidelines, their use or application of the recommendations and disclaims any responsibility for their use or application in any way. The KRF® Guidelines are copyrighted by Keloid Research Foundation. All rights reserved. The KRF Guidelines and the illustrations herein may not be reproduced in any form without the express written permission of KRF®. ©2018.

    KRF Clinical Practice Guidelines for Treatment of Keloids:

    (January 11, 2019) KRF is proud to announce publication of several Keloid Treatment Guidelines. Authoring and production of these Guidelines has been a time-consuming task, yet one that has been long waited for. These Guidelines reflect the most up to date approach to treatment of keloids. We hope that the Guideline allow for establishment of standards in treating keloid patients across the globe. KRF Practice Guidelines.

    3rd International Keloid Symposium:

    (July 15, 2018) KRF is proud to announce that the 2nd was successfully held on June 7-8, 2018 in Rome, Italy with attendees from 22 different countries. During this meeting, KRF was invited to host the 3rd International Keloid Symposium in Beijing. Since the Rome meeting, the organizing committee has worked hard to make this a reality. We are now pleased to announce that our next meeting, the 3rd International Keloid Symposium, which will be a three day meeting will be held in Beijing, China on April 19-21 at the Lecture Hall of the Peking Union Medical College Hospital. Click on the image below to be directed to the symposium website.

    2nd International Keloid Symposium:

    (January 18, 2018) KRF is proudly announcing that the 2nd will be held on June 7-8, 2018 in Rome, Italy. Click on the image below to be directed to the symposium website.

    Notice of 501 (C)(3) Status:

    (February 1, 2017) Keloid Research Foundation has been determined by the US Internal Revenue Service (IRS) to be exempt from federal income tax under Internal Revenue Code (IRC) Section 501(C)(3). Donors can deduct contributions they make to KRF under IRC Section 170. Click here to view the 501(C)(3) Exemption Document.

    Journal of Keloid Research:

    (December 3, 2016)KRF is proud to announce establishment of Keloid Research, an open access scientific publication of the Keloid Research Foundation. Until now, keloid manuscripts have been published in a variety of journals. Our goal is to create a centralized publishing platform for all researchers who are passionate about this disorder, so that relevant clinical and laboratory research can be published in one place and under one umbrella. The journal is aiming to provide an international forum for the publication of original work, describing basic science, translational and clinical investigations in keloid disorder.

    Keloid Staging System:

    (August 19, 2016) In his most recent publication, "Neck Keloids: evaluation of risk factors and recommendation for keloid staging system" Dr. Tirgan has designed a staging system that allows for proper categorization and grouping of keloid patients into various stages.

    To assess each keloid patient properly, to better understand the natural history of this disorder, and to be able to compare future keloid study results among various patients groups, we clearly need a staging system that can allow us to describe the severity keloid disorder based on the size, location and/or extent of the keloidal lesions; as well as history of surgery or radiation therapy, and perhaps other factors that are currently unknown to us. Please click HERE to read more.